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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SP4
All Species:
13.94
Human Site:
S374
Identified Species:
34.07
UniProt:
Q02446
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02446
NP_003103.2
784
81985
S374
A
T
E
S
E
A
Q
S
S
S
Q
L
Q
P
N
Chimpanzee
Pan troglodytes
Q19A40
323
33082
Rhesus Macaque
Macaca mulatta
XP_001101092
866
90913
S456
A
T
E
S
E
A
Q
S
S
S
Q
L
Q
P
N
Dog
Lupus familis
XP_539462
788
82259
S378
A
T
E
S
E
A
Q
S
S
S
Q
L
Q
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q62445
782
81947
S372
A
T
E
S
E
A
Q
S
S
S
Q
L
Q
S
N
Rat
Rattus norvegicus
Q01714
786
80753
N370
L
Q
G
S
D
S
L
N
I
Q
Q
N
Q
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514802
816
85651
N387
S
T
G
I
L
Q
Q
N
T
N
S
L
T
T
S
Chicken
Gallus gallus
Q90WR8
771
80932
D370
Y
I
Q
T
S
V
S
D
D
T
Q
A
Q
N
I
Frog
Xenopus laevis
NP_001083425
767
80109
E371
N
G
L
Q
T
M
S
E
Q
S
N
S
L
Q
Q
Zebra Danio
Brachydanio rerio
NP_956418
714
74632
T336
K
D
N
E
A
D
L
T
Q
S
N
G
L
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.9
90.1
97.9
N.A.
97.3
38.7
N.A.
35.5
41.5
80.9
61.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
26.9
90.1
98.3
N.A.
98
54.8
N.A.
51.3
58.4
88.5
73.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
93.3
20
N.A.
20
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
93.3
N.A.
93.3
46.6
N.A.
53.3
33.3
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
10
40
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
10
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
40
10
40
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
20
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
10
0
20
0
0
0
0
50
20
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
20
0
10
20
10
0
10
40
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% P
% Gln:
0
10
10
10
0
10
50
0
20
10
60
0
60
20
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
50
10
10
20
40
40
60
10
10
0
20
30
% S
% Thr:
0
50
0
10
10
0
0
10
10
10
0
0
10
20
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _